No! Sedation is strictly not allowed by the airlines or recommended by vets.
Apart from the harmful effects that sedation can have on animals (drop of blood pressure for example), airlines want to see that the animal is healthy and well before they get checked in on a flight.
You can help with the anxiety with for example, some herbal sprays that can be used in the crate but owners should check with their vet first. You might want to trial it first to ensure your pet can tolerate the smell in a travel crate for a flight. Talk to our staff or a veterinarian for more specific and suitable advice for your pet.